Open AccessImmunohistochemical evaluation of tumor angiogenesis and the role of mast cells in oral squamous cell carcinoma
Author(s) -
Arpita Kabiraj,
Rakesh Jaiswal,
Anil Singh,
Jagriti Gupta,
Arun S. Singh,
Firoza Samadi
Publication year - 2018
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.163693
Subject(s) - angiogenesis , pathology , immunohistochemistry , mast cell , microvessel , metastasis , staining , haematoxylin , medicine , neovascularization , h&e stain , tumor progression , carcinoma , cancer , cancer research , immunology
Increased angiogenesis has been associated with neoplastic progression, metastasis and outcome in several studies and in a number of malignancies. Among the various host immune cells, mast cells have been implicated in tumor progression by promoting angiogenesis. The aim of this study is to examine the relationship between angiogenesis, mast cells with that of the normal oral mucosa (NOM) and oral squamous cell carcinoma (OSCC).