Open AccessThe effect of mesenchymal stem cells on the p53 methylation in irradiation-induced thymoma in C57BL/6 mice
Author(s) -
Hai B Zheng,
Yan Fu,
Zhen X Pan,
Tong W Yang,
Li Sun,
Yu B. Chen,
Ti Tong
Publication year - 2015
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.160105
Subject(s) - thymoma , biology , microbiology and biotechnology , mesenchymal stem cell , bisulfite sequencing , methylation , immunohistochemistry , dna methylation , cancer research , gene , gene expression , genetics , immunology
Our previous studies showed that mesenchymal stem cells (MSCs) preferentially migrated to irradiation-damaged thymus tissue to maintain the thymus integrity and simultaneously decrease the incidence of thymoma from 57 to 37.5%.