Open AccessGliosarcoma with leiomyomatous differentiation: A case report with an emphasis on histogenesis
Author(s) -
Saumya Shukla,
Namrata P Awasthi,
Pradyumn Singh,
Nuzhat Husain,
Bal Krishna Ojha
Publication year - 2015
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.158026
Subject(s) - histogenesis , gliosarcoma , pathology , biology , medicine , glioblastoma , immunohistochemistry , cancer research
Gliosarcoma is an uncommon high-grade tumor which constitutes about 2% of all glioblastomas. These tumors have the histological hallmark of a biphasic pattern of high-grade glial and sarcomatous components. The histogenesis of these tumors is controversial. We report a case of primary gliosarcoma in an adult male with leiomyomatous differentiation and discuss the histogenesis as it appears in our case. Primary gliosarcomas of the brain are clinically challenging with a poor clinical outcome.