Gliosarcoma with leiomyomatous differentiation: A case report with an emphasis on histogenesis | Zendy

Saumya Shukla | Zendy; Namrata Punit Awasthi | Zendy; Pradyumn Singh | Zendy; Nuzhat Husain | Zendy; Bal Krishna Ojha | Zendy

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Gliosarcoma with leiomyomatous differentiation: A case report with an emphasis on histogenesis

Author(s) -

Saumya Shukla,

Namrata Punit Awasthi,

Pradyumn Singh,

Nuzhat Husain,

Bal Krishna Ojha

Publication year - 2015

Publication title -

journal of cancer research and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 39

eISSN - 0973-1482

pISSN - 1998-4138

DOI - 10.4103/0973-1482.158026

Subject(s) - histogenesis , gliosarcoma , pathology , biology , medicine , glioblastoma , immunohistochemistry , cancer research

Gliosarcoma is an uncommon high-grade tumor which constitutes about 2% of all glioblastomas. These tumors have the histological hallmark of a biphasic pattern of high-grade glial and sarcomatous components. The histogenesis of these tumors is controversial. We report a case of primary gliosarcoma in an adult male with leiomyomatous differentiation and discuss the histogenesis as it appears in our case. Primary gliosarcomas of the brain are clinically challenging with a poor clinical outcome.

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