Open AccessHesperidin inhibits insulin-induced phosphoinositide 3–kinase/Akt activation in human pre-B cell line NALM-6
Author(s) -
Roghayeh Shahbazi,
Makan Cheraghpour,
Reza Homayounfar,
Maryam Nazari,
Javad Nasrollahzadeh,
Sayed Hossein Davoodi
Publication year - 2018
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.157323
Subject(s) - protein kinase b , hesperidin , pi3k/akt/mtor pathway , chemistry , wortmannin , iκb kinase , phosphorylation , kinase , apoptosis , cytotoxic t cell , microbiology and biotechnology , biology , nf κb , biochemistry , medicine , in vitro , alternative medicine , pathology
It has been shown that hesperidin induces apoptosis in NALM-6 cells through inhibition of nuclear factor-kappa B (NF-κB) activation.