Breast carcinoma with numerous large "thanatosomes" | Zendy

ArchanaC Buch | Zendy; NK Panicker | Zendy; AnandR Patel | Zendy

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Breast carcinoma with numerous large "thanatosomes"

Author(s) -

ArchanaC Buch,

NK Panicker,

AnandR Patel

Publication year - 2015

Publication title -

journal of cancer research and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 39

eISSN - 0973-1482

pISSN - 1998-4138

DOI - 10.4103/0973-1482.157304

Subject(s) - hyaline , pathology , eosinophilic , carcinoma , breast carcinoma , pathogenesis , stromal cell , medicine , biology , breast cancer , cancer

Intracytoplasmic and stromal eosinophilic hyaline globules (HGs) have been observed in various neoplastic and nonneoplastic conditions. Thanatosomes are also such HGs seen invariably associated with increased apoptosis and may contain nuclear fragments, occasionally observed in high-grade tumors. We are reporting a case of high-grade breast carcinoma with this striking morphological feature. Their probable nature, pathogenesis, and significance are discussed with review of literature.

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