Open AccessProgressive paraplegia caused by recurrence of mantle-cell lymphoma with atypical spinal magnetic resonance imaging features
Author(s) -
Hiromichi Yamane,
Nobuaki Ochi,
Tomoko Yamagishi,
Nagio Takigawa,
Yoshinobu Maeda
Publication year - 2015
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.154006
Subject(s) - medicine , paraplegia , magnetic resonance imaging , laminectomy , spinal canal , radiology , surgery , mantle cell lymphoma , lymphoma , spinal cord neoplasm , spinal cord , pathology , psychiatry
We describe a case of paraplegia, which had progressed rapidly in a 60-year-old Japanese man with mantle-cell lymphoma. (MCL). He admitted to our hospital due to lumbago and progressive muscle weakness of bilateral lower thighs lasting for 1. month, while he had the history of the systemic chemotherapy for MCL since 10 months. Magnetic resonance imaging. (MRI) revealed a wide-spreading intradural tumor situated in the spinal canal from L1 to L5 with an intervertebral slipped disk as the only site of recurrence. Laminectomy followed by salvage chemotherapy led disappearance of lumbago and paraplegia of the bilateral lower extremities. Although wide-spreading tumor formation in spinal canal without other involvement sites is very rare in MCL, physicians should be aware of such patterns of central nervous system. (CNS) relapse for the early diagnosis and adequate selection of treatment modality