Different effects of the three polymorphisms on 15q25.1 onlung cancer risk: Evidence from published literatures | Zendy

Shukui Wang | Zendy; Huiling Sun | Zendy; Yuqin Pan | Zendy; Bangshun He | Zendy; Qiwen Deng | Zendy; HouQun Ying | Zendy; Jie Chen | Zendy; Xian Liu | Zendy

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Different effects of the three polymorphisms on 15q25.1 onlung cancer risk: Evidence from published literatures

Author(s) -

Shukui Wang,

Huiling Sun,

Yuqin Pan,

Bangshun He,

Qiwen Deng,

HouQun Ying,

Jie Chen,

Xian Liu

Publication year - 2016

Publication title -

journal of cancer research and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 39

eISSN - 0973-1482

pISSN - 1998-4138

DOI - 10.4103/0973-1482.151863

Subject(s) - lung cancer , meta analysis , oncology , medicine , single nucleotide polymorphism , genetic association , lung cancer susceptibility , biology , genotype , genetics , gene

Genetic studies have shown a significant association between lung cancer risk and single nucleotide polymorphisms on chromosome 15q25.1. The potential association of three polymorphisms in the CHRNA3 (rs1051730(G > A)), CHRNA5 (rs16969968(G > A)), and AGPHD1 (rs8034191(A > G)) with the lung cancer risk has been widely investigated, but the results are inconsistent. The aim of meta-analysis was toclarify the link between three polymorphisms and susceptibility to lung cancer.

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