Open AccessAssessment and clinicopathological correlation of p16 expression in head and neck squamous cell carcinoma
Author(s) -
Megha Ralli,
Sunita Singh,
S. P. S. Yadav,
Nisha Sharma,
Renuka Verma,
Rajeev Sen
Publication year - 2016
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.151447
Subject(s) - head and neck squamous cell carcinoma , oncology , correlation , basal cell , medicine , head and neck , head and neck cancer , surgery , cancer , mathematics , geometry
Oral squamous cell carcinoma is a major cause of death throughout the developed world. It is associated with smoking and alcohol consumption. Human papillomavirus (HPV) type 16 has also been suggested to play a role in etiology of head and neck squamous cell carcinoma (HNSCC). p16 expression is now being used as a surrogate marker of HPV infection in squamous cell carcinoma and provides important prognostic information and future therapy planning.