Open AccessInvolvement of syk and VEGF-C in invasion of lung adenocarcinoma A549 cells
Author(s) -
Qing Sun,
Chuanliang Peng,
Bin Cong,
Yingjie Hao,
Jia-zhong Guo,
Yunpeng Zhao,
Xiaogang Zhao
Publication year - 2016
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.150413
Subject(s) - syk , cancer research , a549 cell , adenocarcinoma , lymphangiogenesis , transfection , metastasis , immunohistochemistry , microbiology and biotechnology , lung cancer , biology , tyrosine kinase , pathology , medicine , cancer , immunology , cell culture , signal transduction , genetics
Lung cancer has become one of the most dangerous malignant tumors in the world nowadays, whose pathogenesis is complex involving multi-genes and multi-elements. This study aims to investigate the values of spleen tyrosine kinase (Syk) and vascular endothelial growth factor-C (VEGF-C) in lymphangiogenesis and metastasis of lung adenocarcinoma A549 cells.