Adenocarcinoma of urinary bladder: A report of two patients | Zendy

Usha Agrawal | Zendy; Nitu Kumari | Zendy; Pawan Vasudeva | Zendy; Anup Kumar | Zendy

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Adenocarcinoma of urinary bladder: A report of two patients

Author(s) -

Usha Agrawal,

Nitu Kumari,

Pawan Vasudeva,

Anup Kumar

Publication year - 2015

Publication title -

journal of cancer research and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 39

eISSN - 0973-1482

pISSN - 1998-4138

DOI - 10.4103/0973-1482.148722

Subject(s) - adenocarcinoma , medicine , urinary bladder , prostate , pathology , immunohistochemistry , urology , pathological , oncology , cancer

Adenocarcinoma of the bladder is a rare tumor. Primary and metastatic adenocarcinomas of urinary bladder are morphologically similar, but histogenetically different. We present two cases, a signet ring cell adenocarcinoma with follow-up and another of glandular adenocarcinoma of urinary bladder. Pathological evaluation and immunohistochemical panel of eight markers (E-cadherin, CK20, CK7, CDX2, estrogen receptor (ER), gross cystic disease fluid protein 15 (GCDFP15), 34bE12, and prostate specific antigen (PSA) provides a diagnostic confirmation of primary adenocarcinoma with the positive expression of E-cadherin and CK20 in case 1 and metastatic adenocarcinoma of prostate with profile of E-cadherin+, CK20-, GCDFP15+, 34bE12+, and PSA+ in case 2

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