Abberent expression of oncogenic and tumor-suppressive microRNAs and their target genes in human adenocarcinoma alveolar basal epithelial cells | Zendy

Morteza Karimipoor | Zendy; Elham Tafsiri | Zendy; Mojtaba Darbouy | Zendy; MohammadBehgam Shadmehr | Zendy; WilliamC Cho | Zendy

Open Access

Abberent expression of oncogenic and tumor-suppressive microRNAs and their target genes in human adenocarcinoma alveolar basal epithelial cells

Author(s) -

Morteza Karimipoor,

Elham Tafsiri,

Mojtaba Darbouy,

MohammadBehgam Shadmehr,

WilliamC Cho

Publication year - 2016

Publication title -

journal of cancer research and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 39

eISSN - 0973-1482

pISSN - 1998-4138

DOI - 10.4103/0973-1482.148673

Subject(s) - microrna , a549 cell , biology , gene , adenocarcinoma , cancer research , gene expression , microbiology and biotechnology , complementary dna , cell culture , cancer , genetics

Lung cancer is one of the most serious types of cancer that often diagnosed at advanced stage. MicroRNAs (miRNAs) are small non-coding molecules which silence gene expression of target gene (s) at posttranscriptional level. They are key regulators of cell cycle, apoptosis, anti-cancer drug responsiveness and metastasis.

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