Open AccessCharacterization of immunophenotypic aberrancies in adult and childhood acute lymphoblastic leukemia: A study from Northern India
Author(s) -
Manupriya Sharma,
Man Updesh Singh Sachdeva,
Neelam Varma,
Subhash Varma,
R. K. Marwaha
Publication year - 2016
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.147716
Subject(s) - immunophenotyping , cd117 , cd33 , medicine , myeloid , myeloid leukemia , hematology , cd34 , antigen , bone marrow , pathology , population , immunology , oncology , biology , stem cell , environmental health , genetics
Identification of aberrant antigen expression is important in characterizing neoplastic population among non.neoplastic bone marrow counterparts and further in the detection of minimal residual disease. (MRD). Flow cytometry (FCM) is an important tool in identifying aberrant phenotypes. Incidence of aberrant phenotypes varies considerably in independent studies and its association with prognostic factors is still debatable.