Open AccessTreatment of oral leukoplakia with photodynamic therapy: A pilot study
Author(s) -
Niranzena Panneer Selvam,
Jayachandran Sadaksharam,
Singaravelu Ganesan,
R. Rajasekaran
Publication year - 2015
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.147703
Subject(s) - photodynamic therapy , medicine , leukoplakia , oral leukoplakia , photosensitizer , lesion , dermatology , carcinoma , complete response , cancer , surgery , chemotherapy , photochemistry , chemistry , organic chemistry
Oral leukoplakia (OL) is the most common potentially malignant disorder that may transform into oral carcinoma. By treating leukoplakia in its incipient stage, the risk of occurrence of oral carcinoma can be prevented. In this aspect, photodynamic therapy (PDT) can serve as a useful treatment modality. The aim of the study is to treat patients with OL using PDT in which 5-aminolevulinic acid (ALA) is used as a photosensitizer.