z-logo
open-access-imgOpen Access
Cyclooxygenase-2 expression is associated with elevated aspartate aminotransferase level in hepatocellular carcinoma
Author(s) -
AymanM Metwally,
Eman A. Bayomi,
A S T Barakat,
MahaA El-Bassuoni,
Randa Talaat,
MervatM El-Deftar,
SabrinA Abdel Wahab
Publication year - 2015
Publication title -
journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.147692
Subject(s) - hepatocellular carcinoma , cyclooxygenase , medicine , gastroenterology , chemistry , enzyme , biochemistry
Cyclooxygenase-2 (COX-2), the inducible rate-limiting enzyme of prostaglandins biosynthesis, is involved in the pathogenesis of many chronic inflammation-related human malignancies including hepatocellular carcinoma (HCC). However, its clinical significance in HCC remains obscure. The aim of our study was to evaluate COX-2 expression in HCC and correlate its expression to both clinicopathological parameters and patients survival.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here
Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom