Ligustrazine induces apoptosis of breast cancer cells in vitro and in vivo | Zendy

Guoqin Jiang | Zendy; Jun Pan | Zendy; Jin Shang | Zendy; Zhi-Xue Yang | Zendy

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Ligustrazine induces apoptosis of breast cancer cells in vitro and in vivo

Author(s) -

Guoqin Jiang,

Jun Pan,

Jin Shang,

Zhi-Xue Yang

Publication year - 2014

Publication title -

journal of cancer research and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 39

eISSN - 0973-1482

pISSN - 1998-4138

DOI - 10.4103/0973-1482.147378

Subject(s) - in vivo , apoptosis , in vitro , flow cytometry , pharmacology , cell growth , viability assay , mtt assay , cell culture , chemistry , cancer cell , cell cycle , cancer research , cancer , medicine , biology , immunology , biochemistry , genetics , microbiology and biotechnology

Ligustrazine, the active ingredient present in Umbelliferae plant roots used in Chinese medicine, plays a vital role in reversing multidrug resistance in tumors. This study aims to investigate its anticancer activity and underlying mechanisms in human breast cancer cells in vitro and in vivo.

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