Open AccessIncreased expression of microRNA-301a in nonsmall-cell lung cancer and its clinical significance
Author(s) -
Yugen Shi,
Quan-Ling Zang,
Guixin Li,
Yan Huang,
Shizhong Wang
Publication year - 2016
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.146130
Subject(s) - microrna , medicine , clinical significance , lung cancer , lung , oncology , cancer research , cancer , cell , biology , gene , biochemistry , genetics
Recently, accumulating evidence indicates that dysregulation of microRNAs is associated with the initiation and progression of cancer. Oncogenic miR-301a has been reported upregulation and associated with tumorigenesis and progression in various types of cancer. The aim of this study was to investigate the expression of miR-301a in nonsmall-cell lung cancer. (NSCLC), and to assess its association with malignancy, metastasis and prognosis.