Open AccessLymphatic vessel assessment by podoplanin (D2-40) immunohistochemistry in breast cancer
Author(s) -
Shailja Puri Wahal,
Madhu Mati Goel,
R. M. L. Mehrotra
Publication year - 2015
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.146123
Subject(s) - lymphatic system , lymphatic vessel , lymph , medicine , lymph node , pathology , lymphangiogenesis , podoplanin , immunohistochemistry , breast cancer , cancer , metastasis
Lymph node metastasis has an important bearing on the staging of breast cancer. Lymph node metastasis occurs by hematogenous and lymphatic spread. The hematogenous and lymphatic spread can be quantified by the blood vessel and lymphatic vessel density in the intra-tumoral and peri-tumoral zone by specific markers for blood vessels and lymph vessels.