Open AccessThe clinical value of lymphatic vessel density, intercellular adhesion molecule 1 and vascular cell adhesion molecule 1 expression in patients with oral tongue squamous cell carcinoma
Author(s) -
Junjie Yan,
Yushi Jiang,
Min Ye,
Weidong Liu,
Liang Feng
Publication year - 2014
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.145827
Subject(s) - lymphatic system , lymphatic vessel , lymphatic endothelium , pathology , tongue , cell adhesion molecule , intercellular adhesion molecule 1 , immunohistochemistry , vcam 1 , metastasis , biology , icam 1 , cancer , medicine , microbiology and biotechnology
Oral tongue squamous cell carcinoma (OTSCC) is an oral carcinoma prone to lymphatic metastasis. Intercellular adhesion molecule 1 (ICAM-1) and vascular cell adhesion molecule 1 (VCAM-1) as important adhesion molecules play roles in regulating cell-cell adhesion and tumor cells metastasis.