Open AccessRaynaud′s phenomenon in a child with medulloblastoma as a late effect of chemotherapy
Author(s) -
Erman Ataş,
Nadir Korkmazer,
Hatice A Artik,
Oğuzhan Babacan,
Vural Kesik
Publication year - 2015
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.144649
Subject(s) - bleomycin , vinblastine , vincristine , medicine , medulloblastoma , cisplatin , chemotherapy , vinca , toxicity , oncology , pharmacology , cyclophosphamide , pathology
There are a lot of early or late side effects of chemotherapies. One of them is Raynaud′s phenomenon (RP). Vascular toxicity associated with antineoplastic agents is notified in bleomycin alone therapy or in combination with cisplatin, vinblastine, and vincristine. The mechanism of RP associated with antineoplastic agents is unknown. All children receiving vinblastine, vincristine, bleomycin and cisplatin therapy, are followed and questioned about their complaint on RP. Long-term follow-up of surviving patients is recommended. Oncologists should be aware of the potential late toxic effects of antineoplastic drugs