Open AccessConstruction and analysis of the regulatory network disturbed by the silenced Sp1 transcription factor in HeLa cells
Author(s) -
Fengyan Li,
Lijun Yu,
Li Li,
Meiyan Wei
Publication year - 2015
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.140811
Subject(s) - hela , transcription factor , sp1 transcription factor , microbiology and biotechnology , cancer research , promoter , biology , genetics , gene , cell culture , gene expression
The objective of our study was to explore the characteristics of the regulatory network after siRNA-Sp1 (Specificity Protein 1) treatment in HeLa cells through the regulation network construction with bioinformatics methods.