Open AccessWell-differentiated fetal adenocarcinoma of the lung in an adult male: Report of an unusual tumor with a brief review of literature
Author(s) -
Rashmi Patnayak,
Amitabh Jena,
N Rukmangadha,
AY Lakshmi,
Abha Chandra
Publication year - 2014
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.136677
Subject(s) - malignancy , adenocarcinoma , fetus , lung , medicine , pathology , immunohistochemistry , adenocarcinoma of the lung , cancer , biology , pregnancy , genetics
We report a case of a well-differentiated fetal adenocarcinoma (WDFA) of the lung in a 50-year-old male smoker. The literature regarding this uncommon tumor is limited. This rare variant of adenocarcinoma is more common in females, in the third and fourth decades. Microscopically it is composed of neoplastic glands and tubules that resemble the fetal lung. Well-differentiated fetal adenocarcinoma is a low-grade malignancy and surgery is the preferred mode of therapy. This uncommon case of a well-differentiated fetal adenocarcinoma in an adult male patient is reported, with relevant immunohistochemical findings, along with a discussion of the current literature.