
Retroperitoneal ancient schwannoma: Two cases and review of literature
Author(s) -
Ranganath Ratnagiri,
Sai Mallikarjun
Publication year - 2014
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.136660
Subject(s) - neurilemoma , schwannoma , nuclear atypia , medicine , atypia , pathology , immunohistochemistry
Ancient Schwannomas are rare variants of tumors which arise from the peri-neural Schwann cells. These tumors are termed "ancient" because of the degenerative features acquired with increasing age in these tumors. They are benign, slow growing and usually detected only incidentally or due to local symptoms. Some tumors may demonstrate nuclear atypia, and may be mistakenly termed malignant. Malignant change is usually associated with von Recklinghausen's syndrome in 5% to 18% of cases. Retroperitoneal schwannomas account for only 0.5% to 5% of all cases and are extremely uncommon. They are well encapsulated and recurrences following complete surgical excision are uncommon.