Open AccessPrognostics of Cyclin-D1 expression with chemoradiation response in patients of locally advanced oral squamous cell carcinoma
Author(s) -
Huma Khan,
Seema Gupta,
Nuzhat Husain,
Sanjeev Misra,
Navneet Singh,
Mahendra Pal Singh Negi
Publication year - 2014
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.136549
Subject(s) - cyclin d1 , medicine , oncology , stage (stratigraphy) , lymph node , immunohistochemistry , cell cycle , cancer research , cancer , biology , paleontology
Cyclin-D1 has been strongly implicated in cell cycle proliferation particularly in the G1/S checkpoint in the cell cycle, and prognosis in many human malignancies. The present study evaluates its prognostic significance with chemoradiation response in patients of locally advanced oral squamous cell carcinoma (OSCC).