Absence of correlation between serum CRP levels and mitochondrial D-loop DNA mutations in gastro-oesophageal adenocarcinoma | Zendy

BenjaminH. L. Tan | Zendy; RichardJ. E. Skipworth | Zendy; Nick Wheelhouse | Zendy; KennethC. H. Fearon | Zendy; J Stuart Ross | Zendy

Open Access

Absence of correlation between serum CRP levels and mitochondrial D-loop DNA mutations in gastro-oesophageal adenocarcinoma

Author(s) -

BenjaminH. L. Tan,

RichardJ. E. Skipworth,

Nick Wheelhouse,

KennethC. H. Fearon,

J Stuart Ross

Publication year - 2014

Publication title -

journal of cancer research and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 39

eISSN - 0973-1482

pISSN - 1998-4138

DOI - 10.4103/0973-1482.131458

Subject(s) - mitochondrial dna , adenocarcinoma , carcinogenesis , mutation , biology , cancer , d loop , gastro , mutation frequency , microbiology and biotechnology , cancer research , gastroenterology , pathology , genetics , medicine , gene , disease , reflux

Both inflammation and mitochondrial DNA (mtDNA) mutation are thought to play a role in the many human cancers. The aim of this study was to evaluate the relationship between inflammation and accumulation of mitochondrial DNA (mtDNA) mutations in the D-loop region in carcinogenesis of gastro-oesophageal adenocarcinomas.

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