Open AccessValidation of a high-performance liquid chromatographic ultraviolet detection method for the quantification of vandetanib in rat plasma and its application to pharmacokinetic studies
Author(s) -
Hongjun Lin,
Dandan Cui,
Zhixing Cao,
Qian Bu,
Xu YouZhi,
Yinglan Zhao
Publication year - 2014
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.131393
Subject(s) - vandetanib , chromatography , pharmacokinetics , high performance liquid chromatography , chemistry , triethylamine , acetonitrile , pharmacology , medicine , receptor , biochemistry , organic chemistry , tyrosine kinase
To develop a simple and sensitive high-performance liquid chromatography (HPLC) assay with ultraviolet detection method of vandetanib in rat plasma.