Validation of a high-performance liquid chromatographic ultraviolet detection method for the quantification of vandetanib in rat plasma and its application to pharmacokinetic studies | Zendy

Yinglan Zhao | Zendy; Hongjun Lin | Zendy; Dandan Cui | Zendy; Zhixing Cao | Zendy; Qian Bu | Zendy; Youzhi Xu | Zendy

Open Access

Validation of a high-performance liquid chromatographic ultraviolet detection method for the quantification of vandetanib in rat plasma and its application to pharmacokinetic studies

Author(s) -

Yinglan Zhao,

Hongjun Lin,

Dandan Cui,

Zhixing Cao,

Qian Bu,

Youzhi Xu

Publication year - 2014

Publication title -

journal of cancer research and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 39

eISSN - 0973-1482

pISSN - 1998-4138

DOI - 10.4103/0973-1482.131393

Subject(s) - vandetanib , chromatography , pharmacokinetics , high performance liquid chromatography , chemistry , triethylamine , acetonitrile , pharmacology , medicine , receptor , biochemistry , organic chemistry , tyrosine kinase

To develop a simple and sensitive high-performance liquid chromatography (HPLC) assay with ultraviolet detection method of vandetanib in rat plasma.

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