Open AccessThe role of mast cells and angiogenesis in well-differentiated oral squamous cell carcinoma
Author(s) -
Ali Tahir,
A. H. Nagi,
Ehsan Ullah,
Omer Sefvan Janjua
Publication year - 2013
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.119311
Subject(s) - angiogenesis , mast cell , metastasis , pathology , stain , basal cell , cell , carcinoma , biology , cancer research , medicine , immunology , staining , cancer , genetics
Neo-vascularization is vital for an expansion and metastasis of a tumor and is influenced by a number of mediators. Mast cells are believed to release many pro-angiogenic mediators that may help in tumor expansion and invasion. This study describes the role of mast cells and angiogenesis in oral squamous cell carcinoma (OSCC).