Open AccessAberrant expression of trefoil factor 3 is associated with colorectal carcinoma metastasis
Author(s) -
Yang H. Huang,
Yunfeng Li,
Liping Wang,
Yun Zhang
Publication year - 2013
Publication title -
journal of cancer research and therapeutics (online)
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.119308
Subject(s) - colorectal cancer , immunohistochemistry , medicine , carcinogenesis , pathology , oncology , metastasis , lymph node , cancer , cancer research
Recent evidence has indicated that the trefoil factor family possesses pivotal roles in the progression of human cancer. Aberrant expression of trefoil factor 3 (TFF3) has been reported to correlate with an aggressive tumor phenotype. However, the clinical importance of TFF3 expression in colorectal carcinomas (CRCs) has rarely been addressed.