Open AccessSmall cell variant of anaplastic large cell lymphoma presenting as arm mass in a child: A rare entity with diagnostic challenge
Author(s) -
Sunil Pasricha,
Jatin Gandhi,
Gurudutt Gupta,
Anurag Mehta
Publication year - 2013
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.113410
Subject(s) - anaplastic large cell lymphoma , lymphoma , immunohistochemistry , medicine , differential diagnosis , anaplastic lymphoma kinase , pathology , large cell , cell , biology , cancer , adenocarcinoma , genetics , malignant pleural effusion , lung cancer
Anaplastic lymphoma kinase positive, anaplastic large cell lymphoma (ALCL) is an uncommon T-cell non-Hodgkin lymphoma. A rare morphological variant-small cell variant of ALCL may pose diagnostic challenge especially when it presents primarily as a soft tissue mass. We present a rare case of small cell variant of ALCL in a 14-year-old female presented with arm swelling with emphasis on clinical, morphological and immunohistochemical aspects. Pathologists should be aware of this entity when considering a differential diagnosis of malignant round cell tumor as early and correct diagnosis has important clinical implications.