Genetic polymorphisms of xeroderma pigmentosum group D and prostate cancer risk: A meta-analysis | Zendy

Hongxia Ma | Zendy; Hongcheng Zhu | Zendy; Songyu Cao | Zendy; Yun Liu | Zendy; Xiangxiang Ding | Zendy; Qianqian Wu | Zendy

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Genetic polymorphisms of xeroderma pigmentosum group D and prostate cancer risk: A meta-analysis

Author(s) -

Hongxia Ma,

Hongcheng Zhu,

Songyu Cao,

Yun Liu,

Xiangxiang Ding,

Qianqian Wu

Publication year - 2013

Publication title -

journal of cancer research and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 39

eISSN - 0973-1482

pISSN - 1998-4138

DOI - 10.4103/0973-1482.113345

Subject(s) - xeroderma pigmentosum , ercc2 , prostate cancer , odds ratio , oncology , meta analysis , medicine , allele , genotype , nucleotide excision repair , confidence interval , single nucleotide polymorphism , cancer , genetics , biology , dna repair , gene

The Xeroderma pigmentosum group D (XPD, also referred to as excision repair cross complementing gene 2, ERCC2) is one of key genes involved in nucleotide excision repair and two potentially functional polymorphisms of XPD (Asp312Asn and Lys751Gln) have been widely investigated in various cancers including prostate cancer. However, the results were conflicting rather than conclusive.

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