Open AccessGenetic polymorphisms of xeroderma pigmentosum group D and prostate cancer risk: A meta-analysis
Author(s) -
Hongcheng Zhu,
Shougen Cao,
Yun Liu,
Xiangxiang Ding,
Qianqian Wu,
Hongxia Ma
Publication year - 2013
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.113345
Subject(s) - xeroderma pigmentosum , ercc2 , prostate cancer , odds ratio , oncology , meta analysis , medicine , allele , genotype , nucleotide excision repair , confidence interval , single nucleotide polymorphism , cancer , genetics , biology , dna repair , gene
The Xeroderma pigmentosum group D (XPD, also referred to as excision repair cross complementing gene 2, ERCC2) is one of key genes involved in nucleotide excision repair and two potentially functional polymorphisms of XPD (Asp312Asn and Lys751Gln) have been widely investigated in various cancers including prostate cancer. However, the results were conflicting rather than conclusive.