Open AccessExtranodal Rosai-Dorfman Disease presenting as spinal extradural lesion: A case report with a review of the literature
Author(s) -
Chhaya Roy,
Atanu Saha,
Subhendu Roy,
Asish Kumar Ghosh
Publication year - 2012
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.106588
Subject(s) - medicine , rosai–dorfman disease , lesion , sinus histiocytosis with massive lymphadenopathy , laminectomy , magnetic resonance imaging , spinal disease , radiology , presentation (obstetrics) , spinal cord , surgery , disease , pathology , lumbar , psychiatry
Sinus histiocytosis with massive lymphadenopathy (SHML) or Rosai-Dorfman disease (RDD) is a rare, but well-documented entity. We report a male patient who presented with progressive paraparesis, with thoracolumbar extradural lesion (from D11 to L2 level) on magnetic resonance imaging (MRI). He underwent D12-L2 laminectomy followed by total removal of extradural spinal space-occupying lesion (SOL). Histopathological diagnosis of the lesion was RDD. Four weeks after surgery, he was treated with external beam radiotherapy, total dose: 50.4GY in 28 fractions. On three-month follow-up, he did not have any neurological deficits. There was no evidence of other extranodal or lymph node involvement. This case has been reported on account of rare presentation of this disease as spinal extradural lesion. Pertinent literature has been reviewed.