Immunohistochemical expression of IDH1 in gliomas: A tissue microarray-based approach | Zendy

Avninder Singh | Zendy; Varuna Sipayya | Zendy; Ira Sharma | Zendy; KC Sharma | Zendy

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Immunohistochemical expression of IDH1 in gliomas: A tissue microarray-based approach

Author(s) -

Avninder Singh,

Varuna Sipayya,

Ira Sharma,

KC Sharma

Publication year - 2012

Publication title -

journal of cancer research and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 39

eISSN - 0973-1482

pISSN - 1998-4138

DOI - 10.4103/0973-1482.106567

Subject(s) - idh1 , immunohistochemistry , isocitrate dehydrogenase , glioma , pathology , astrocytoma , tissue microarray , oligodendroglioma , monoclonal antibody , ependymoma , biology , cancer research , medicine , antibody , immunology , mutant , gene , enzyme , biochemistry

Mutations in the gene encoding isocitrate dehydrogenase (IDH1) have been reported in gliomas. This study analyses a series of 184 glioma cases in a tissue microarray (TMA)-based approach to assess the frequency of R132H point mutations in formalin-fixed, paraffin-embedded tissue samples.

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