Open AccessImmunohistochemical correlation of epidermal growth factor receptor and c-erbB-2 with histopathologic grading of mucoepidermoid carcinoma
Author(s) -
Monir Moradzadeh Khiavi,
Sepideh Vosoughhosseini,
Shirin Saravani,
Monireh Halimi
Publication year - 2012
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.106550
Subject(s) - mucoepidermoid carcinoma , grading (engineering) , immunohistochemistry , pathology , salivary gland , medicine , carcinoma , epidermal growth factor receptor , malignancy , biology , cancer , ecology
Mucoepidermoid carcinoma is the most common salivary gland malignancy with highly variable biologic potential that correlates with the histopathologic grade of the tumor. Therefore, identification of the histopathologic grade of the mucoepidermoid carcinoma is very important in the treatment and determination of the final prognosis. The present study was performed to survey immunohistochemically Epidermal Growth Factor ReceptorEGFR and c-erbB-2 expression in different grades of mucoepidermoid carcinoma.