Open AccessValue of bone marrow examination in Hodgkin lymphoma: Report of three cases with review of literature
Author(s) -
Jyoti R. Kini,
Pooja K Suresh,
Ruchi Sinha,
Kausalya Kumari Sahu,
Suneet Kumar,
Krishna Prasad
Publication year - 2012
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.103535
Subject(s) - medicine , bone marrow , lymphoma , trephine , stage (stratigraphy) , bone marrow examination , incidence (geometry) , biopsy , disease , hodgkin lymphoma , pathology , paleontology , physics , optics , biology
Bone marrow involvement by Hodgkin lymphoma is rare with an average incidence of 10%. However, the incidence of bone marrow involvement has been shown to be less than 1% in patients with clinical stage IA or IIA disease. The involvement of the marrow in a patient with Hodgkin lymphoma represents stage IV disease. We report our experience wherein three cases of marrow involvement were picked up on bone marrow aspirates/ -imprints and confirmed on trephine biopsy. In this paper we wish to highlight the significance of bone marrow examination in the initial diagnosis and staging of even clinically early stage Hodgkin lymphoma. Staging investigations performed at the time of diagnosis for patients with Hodgkin lymphoma are vital for determining the appropriate treatment and prognosis.