Open AccessMethylenetetrahydrofolate reductase gene polymorphisms (677C > T and 1298A > C) in Egyptian patients with non-hodgkin lymphoma
Author(s) -
Ahmed Nasr,
Rania M. Sami,
N. A. Ibrahim
Publication year - 2012
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.103512
Subject(s) - methylenetetrahydrofolate reductase , genotype , gastroenterology , medicine , allele , lymphoma , restriction fragment length polymorphism , genetics , biology , gene
Folate metabolism plays an essential role in Deoxyribonucleic acid (DNA) synthesis and methylation processes. Deviations in the flux of the folate may affect the susceptibility to various cancers including lymphoma.