Open AccessIrradiation-mediated carbon nanotubes′ use in cancer therapy
Author(s) -
Jin-Gang Yu,
Feipeng Jiao,
Xiaoqing Chen,
Xinyu Jiang,
Zhiguang Peng,
Dongming Zeng,
Dushu Huang
Publication year - 2012
Publication title -
journal of cancer research and therapeutics/journal of cancer research and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 39
eISSN - 0973-1482
pISSN - 1998-4138
DOI - 10.4103/0973-1482.103511
Subject(s) - bioavailability , drug delivery , drug , in vivo , cancer , cancer therapy , pharmacology , carbon nanotube , cancer treatment , anticancer drug , medicine , nanotechnology , materials science , biology , microbiology and biotechnology
Anticancer drugs such as biological therapeutic proteins and peptides are used for treatment of a variety of tumors. However, their wider use has been hindered by their poor bioavailability and the uncontrollable sites of action in vivo. Cancer nano-therapeutics is rapidly progressing, which is being applied for solving some limitations of conventional drug delivery systems. To improve the bio-distribution of anticancer drugs, carbon nanotubes have been used as one of the most effective drug carriers. This review discusses the carbon nanotubes-mediated methods for the delivery of anticancer drugs, with emphasis on the radiation-induced drug-targeted releasing and selective photo-thermal cancer therapy.