Open AccessDepolarizing effects of daikenchuto on interstitial cells of Cajal from mouse small intestine
Author(s) -
Hyungwoo Kim,
Hyun Jung Kim,
Dongki Yang,
Myeong Ho Jung,
Byung Joo Kim
Publication year - 2017
Publication title -
pharmacognosy magazine
Language(s) - English
Resource type - Journals
eISSN - 0976-4062
pISSN - 0973-1296
DOI - 10.4103/0973-1296.196312
Subject(s) - interstitial cell of cajal , methoctramine , depolarization , pacemaker potential , muscarinic acetylcholine receptor , muscarinic acetylcholine receptor m3 , medicine , antagonist , receptor antagonist , receptor , endocrinology , small intestine , pharmacology , chemistry , immunohistochemistry
Daikenchuto (DKT; TJ-100, TU-100), a traditional herbal medicineis used in modern medicine to treat gastrointestinal (GI) functional disorders. Interstitial cells of Cajal (ICCs) are the pacemaker cells of the GI tract and play important roles in the regulation of GI motility.