Open AccessPostprandial antihyperglycemic and antioxidant activities of Acalypha indica Linn stem extract: An in-vivo study
Author(s) -
Charles Lekhya Priya,
Kokati Venkata Bhaskara Rao
Publication year - 2016
Publication title -
pharmacognosy magazine
Language(s) - English
Resource type - Journals
eISSN - 0976-4062
pISSN - 0973-1296
DOI - 10.4103/0973-1296.191461
Subject(s) - postprandial , streptozotocin , antioxidant , maltose , diabetes mellitus , sucrose , medicine , blood sugar , ingestion , carbohydrate , traditional medicine , oxidative stress , pharmacology , chemistry , endocrinology , food science , biochemistry
α-glucosidase inhibitors controls postprandial hyperglycemia (PPHG) by lowering sharp rise in blood glucose levels after ingestion of carbohydrate rich meal in type 2 diabetic (T2D) individuals. Acalypha indica commonly known as Indian copper leaf is used in traditional medicinal system to treat various diseases. In our previous in-vitro investigation, methanolic extract of A. indica stems (AIS) proved to be an effective a-glucosidase inhibitor, antioxidant, and well tolerated in acute and subchronic toxicity studies in albino wistar rats.