Open AccessFlavonoids derived from Abelmoschus esculentus attenuatesUV-B Induced cell damage in human dermal fibroblasts throughNrf2-ARE pathway
Author(s) -
Juilee Patwardhan,
Purvi Bhatt
Publication year - 2016
Publication title -
pharmacognosy magazine
Language(s) - English
Resource type - Journals
eISSN - 0976-4062
pISSN - 0973-1296
DOI - 10.4103/0973-1296.182175
Subject(s) - antioxidant , oxidative stress , reactive oxygen species , rutin , chemistry , dna damage , abelmoschus , biochemistry , flavonoid , cytotoxicity , pharmacology , intracellular , biology , dna , in vitro , agronomy
Ultraviolet-B (UV-B) radiation is a smaller fraction of the total radiation reaching the Earth but leads to extensive damage to the deoxyribonucleic acid (DNA) and other biomolecules through formation of free radicals altering redox homeostasis of the cell. Abelmoschus esculentus (okra) has been known in Ayurveda as antidiabetic, hypolipidemic, demulscent, antispasmodic, diuretic, purgative, etc.