Open AccessNaringin and rutin alleviates episodic memory deficits in two differentially challenged object recognition tasks
Author(s) -
Grandhi Venkata Ramalingayya,
Madhavan Nampoothiri,
Pawan G. Nayak,
Anoop Kishore,
Rekha R Shenoy,
Mallikarjuna Rao Chamallamudi,
Krishnadas Nandakumar
Publication year - 2016
Publication title -
pharmacognosy magazine
Language(s) - English
Resource type - Journals
eISSN - 0976-4062
pISSN - 0973-1296
DOI - 10.4103/0973-1296.176104
Subject(s) - episodic memory , neuroprotection , naringin , donepezil , psychology , medicine , neuroscience , recognition memory , neurocognitive , cognition , dementia , disease , biology , genetics
Cognitive decline or dementia is a debilitating problem of neurological disorders such as Alzheimer's and Parkinson's disease, including special conditions like chemobrain. Dietary flavonoids proved to be efficacious in delaying the incidence of neurodegenerative diseases. Two such flavonoids, naringin (NAR) and rutin (RUT) were reported to have neuroprotective potential with beneficial effects on spatial and emotional memories in particular. However, the efficacy of these flavonoids is poorly understood on episodic memory, which comprises an important form of autobiographical memory.