Open AccessPoncirus trifoliata Rafin. induces the apoptosis of triple-negative breast cancer cells via activation of the c-Jun NH(2)-terminal kinase and extracellular signal-regulated kinase pathways
Author(s) -
Hogyu Han,
Mi Heon Ryu,
Yonghae Son,
Guemsan Lee,
Seung-Hwa Jeong,
Hyungwoo Kim
Publication year - 2015
Publication title -
pharmacognosy magazine
Language(s) - English
Resource type - Journals
eISSN - 0976-4062
pISSN - 0973-1296
DOI - 10.4103/0973-1296.166056
Subject(s) - kinase , triple negative breast cancer , mapk/erk pathway , cancer research , c jun , tradd , apoptosis , cancer cell , cancer , death domain , necroptosis , survivin , breast cancer , extracellular , chemistry , programmed cell death , medicine , biology , microbiology and biotechnology , biochemistry , gene , transcription factor
Poncirus trifoliata Rafin. is a traditional medicine with known anti-inflammatory and anti-cancer properties. Traditionally, it is used to control chronic inflammation, allergy and gastrointestinal diseases such as digestive ulcers gastritis in China, Japan, and Korea.