Open AccessAnti-tumor activity of safranal against neuroblastoma cells
Author(s) -
Saeed Samarghandian,
Mohammad Ebrahim Shoshtari,
Javad Sargolzaei,
Hosna Hossinimoghadam,
Farahzad Jabbari Azad
Publication year - 2014
Publication title -
pharmacognosy magazine
Language(s) - English
Resource type - Journals
eISSN - 0976-4062
pISSN - 0973-1296
DOI - 10.4103/0973-1296.133296
Subject(s) - safranal , propidium iodide , neuroblastoma , apoptosis , flow cytometry , cell culture , chemistry , cell growth , cell cycle , programmed cell death , cancer research , microbiology and biotechnology , pharmacology , biology , biochemistry , crocin , genetics
Safranal (2,6,6-trimethyl-1,3-cyclohexadiene-1-carboxaldehyde, C10H14O) is an active ingredient in the saffron, which is used in traditional medicine, and also, the biological activity of saffron in anti-cancer is in development. It has been reported to have anti-oxidant effects, but its anti-tumor effects remain uncertain. The aim of this study was to evaluate effects of safranal on anti-tumor on neuroblastoma cells.