Open AccessAnesthetic management of a child with autistic spectrum disorder and homocysteinemia
Author(s) -
Deepak Choudhary,
Ghansham Biyani,
Pradeep Bhatia,
Nikhil Kothari
Publication year - 2016
Publication title -
the indian anaesthetists' forum
Language(s) - English
Resource type - Journals
eISSN - 2589-7934
pISSN - 0973-0311
DOI - 10.4103/0973-0311.183573
Subject(s) - hypoglycemia , anesthetic , medicine , refractory (planetary science) , anesthesia , pediatrics , biology , astrobiology , insulin
Autistic spectrum disorder (ASD) is a developmental disability of the central nervous system with rapid worsening. A subset of patients also has mitochondrial dysfunction leading to increased sensitivity to various anesthetic agents. Rarely, gene mutation in these patients results in homocysteinemia which causes higher incidences of thromboembolism, hypoglycemia, and seizures. Anesthetic management of ASD with homocysteinemia and refractory seizures has not been previously reported