Open AccessReview of paraneoplastic syndromes associated with oropharyngeal squamous cell carcinoma
Author(s) -
Deepu George Mathew,
Rooban Thavarajah,
V Janani,
Elizabeth Joshua,
UK Rao,
Kannan Ranganathan
Publication year - 2010
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/0973-029x.72499
Subject(s) - malignancy , medicine , head and neck , basal cell , broad spectrum , dermatology , pathology , oncology , surgery , chemistry , combinatorial chemistry
Malignancies are usually preceded by the presence of various paraneoplastic syndromes (PNS), which could be the indirect and/or remote effects of the metabolites produced by neoplastic cells. PNS manifested by oropharyngeal squamous cell carcinomas, which is the most common head and neck malignancy, are highlighted in this review. Knowledge of the clinical spectrum of these syndromes will equip the oral physician for early diagnosis and management of these hidden malignancies, especially of the pharyngeal region.