Open AccessAmelogenesis imperfecta: Report of a case and review of literature
Author(s) -
Mayur Chaudhary,
Shweta Dixit,
Amit Shankar Singh,
Sanket Kunte
Publication year - 2009
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/0973-029x.57673
Subject(s) - amelogenesis imperfecta , enamel paint , amelogenesis , amelogenin , osteogenesis imperfecta , inheritance (genetic algorithm) , ameloblast , genetics , tooth enamel , biology , dentistry , gene , medicine , anatomy , orthodontics
Amelogenesis imperfecta (AI) is a diverse collection of inherited diseases that exhibit quantitative or qualitative tooth enamel defects in the absence of systemic manifestations. Also known by varied names such as Hereditary enamel dysplasia, Hereditary brown enamel, Hereditary brown opalescent teeth, this defect is entirely ectodermal, since mesodermal components of the teeth are basically normal. The AI trait can be transmitted by either autosomal dominant, autosomal recessive, or X-linked modes of inheritance. Genes implicated in autosomal forms are genes encoding enamel matrix proteins, namely: enamelin and ameloblastin, tuftelin, MMP-20 and kallikrein - 4. This article presents a case reported to Dr. D. Y. Patil, Dental College and Hospital, Pune, India, along with a review of this often seen clinical entity.