Open AccessAn in vitro study of isolation of candidal strains in oral squamous cell carcinoma patients undergoing radiation therapy and quantitative analysis of the various strains using CHROMagar
Author(s) -
Mohammad Mohsin Abdul Razak Ainapur,
Pushpalatha Mahesh,
K. V. S. Hari Kumar,
Abhishek Deepak,
Ujjwal Mrinal,
Swayam Prakash
Publication year - 2017
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/0973-029x.203793
Subject(s) - radiation therapy , candida tropicalis , medicine , candida krusei , candida albicans , cancer , oral cavity , basal cell , gastroenterology , microbiology and biotechnology , oncology , biology , dentistry
Patients undergoing radiation therapy for oral squamous cell carcinoma (OSCC) have an increased risk of developing oral candidiasis. Radiation-induced hyposalivation is thought to be a major predisposing factor for it. Radiation therapy for 2-3 weeks leads to increase in the number of candidal species in the oral cavity, eventually leading to oral candidiasis.