Open AccessQuantification of Porphyromonas gingivalis in chronic periodontitis patients associated with diabetes mellitus using real-time polymerase chain reaction
Author(s) -
G V Padmalatha,
Radhika M Bavle,
Gadavalli Vera Venkata Satyakiran,
K Paremala,
M Sudhakara,
Soumya Makarla
Publication year - 2016
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/0973-029x.190933
Subject(s) - porphyromonas gingivalis , periodontitis , diabetes mellitus , medicine , chronic periodontitis , prevotella intermedia , polymerase chain reaction , dentistry , periodontium , etiology , tooth loss , gastroenterology , biology , endocrinology , gene , biochemistry , oral health
Periodontal diseases, if left untreated, can lead to tooth loss and affect at least one tooth in 80% of adults worldwide, with the main cause being a bacterial plaque. Among subgingival plaque bacterial species, Porphyromonas gingivalis has been implicated as a major etiological agent causing tooth loss. Diabetics and smokers are two patient groups at high risk for periodontal disease. The increase in the number of this organism with the coexistence of other pathogenic microbes leads to rapid destruction of the periodontium, premature loss of teeth and also because of its virulence has implications in systemic pathology. Our aim was to observe the involvement of P. gingivalis in diabetes mellitus (DM) patients associated with periodontitis with and without tobacco-associated habits and to compare them with periodontitis patients having no other systemic pathologies.