Open AccessEvaluation of homocysteine levels in individuals having nonsyndromic cleft lip with or without palate
Author(s) -
Riaz Abdulla,
Rouchelle Tellis,
Roshan Athikari,
Jagadish Kudkuli
Publication year - 2016
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/0973-029x.190910
Subject(s) - homocysteine , medicine , context (archaeology) , statistical significance , neural tube , gastroenterology , dentistry , biology , genetics , embryo , paleontology
Nonsyndromic cleft lip with or without palate (NSCL ± P) is a genetic predisposition involving defects in shape and makeup of the lip and palate. Elevation of homocysteine (Hcy) levels is seen in medical complications such as developmental anomalies causing neural tube defects, congenital vascular diseases, neurodegenerative and psychiatric conditions. Evaluation of serum Hcy levels forms an important feature to look further into molecular aspects.