Open AccessEvaluation of natural killer cell (CD57) as a prognostic marker in oral squamous cell carcinoma: An immunohistochemistry study
Author(s) -
Rashmi Agarwal,
Minal Chaudhary,
Shruti Bohra,
Shree Bajaj
Publication year - 2016
Publication title -
journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/0973-029x.185933
Subject(s) - immunohistochemistry , pathology , basal cell , natural killer cell , cell , immune system , carcinoma , medicine , biology , immunology , cytotoxic t cell , in vitro , biochemistry , genetics
Natural killer (NK) cells are important effector lymphocytes. NK cells are considered to represent innate immune system. NK cells target and kill aberrant cells such as virally infected and tumorigenic cells. The purpose of this study was to assess the expression of CD57 in oral squamous cell carcinoma (OSCC) and to correlate the expression of CD57 with 3 years survival in patients with OSCC.