Open Accessβ catenin in health: A review
Author(s) -
Swayam Prakash,
Uma Swaminathan
Publication year - 2015
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/0973-029x.164537
Subject(s) - wnt signaling pathway , catenin , lrp6 , microbiology and biotechnology , biology , lrp5 , secretion , signal transduction , glycoprotein , beta catenin , genetics , biochemistry
β catenin belongs to the armadillo family of proteins. It plays a crucial role in developmental and homeostatic processes. Wnts are a family of 19 secreted glycoproteins that transduce multiple signaling cascades, including the canonical Wnt/β catenin pathway, Wnt/Ca(2+) pathway and the Wnt/polarity pathway. This is a review on β catenin, Wnt proteins and their secretion, the signaling pathway, the associated factors and the crucial role of β catenin in odontogenesis.