Open AccessAmeloblastic carcinoma of the mandible: Report of a case and review
Author(s) -
Shreenivas Kallianpur,
Sanjay Jadwani,
Biswajit Misra,
Udyavara Sridhara Sudheendra
Publication year - 2014
Publication title -
journal of oral and maxillofacial pathology/journal of oral and maxillofacial pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.455
H-Index - 25
eISSN - 1998-393X
pISSN - 0973-029X
DOI - 10.4103/0973-029x.141336
Subject(s) - histogenesis , malignancy , mandible (arthropod mouthpart) , ameloblastoma , odontogenic tumor , medicine , lesion , pathology , immunohistochemistry , maxilla , biology , anatomy , botany , genus
Ameloblastic carcinoma is a rare malignant odontogenic neoplasm that can arise either as a de novo lesion or from pre-existing ameloblastoma. Histopathologically, the tumor retains an ameloblastomatous differentiation pattern but shows cytological features of malignancy. Owing to variable biologic behavior and paucity of long-term follow-up cases, there has been no clear consensus on treatment protocol. The present case of ameloblastic carcinoma arose in the mandible of a 24-year-old male. Surgical treatment involved resection of the mandible along with regional lymph nodes. The patient has been on follow up for the past one year without any recurrence or metastases. An update on ameloblastic carcinoma encompassing the histogenesis, immunohistochemical features and treatment aspects are included.